The September/October issue of Health Affairs (“Overhauling the Delivery System,” Volume 27, Number 5) contains a full section devoted to disruptive innovation in health care delivery. An article from Hwang and Christensen, entitled “Disruptive Innovation in Health Care Delivery: A Framework for Business-Model Innovation,” leads off the discussion. A press conference was held in Washington, D.C. on September 10, 2008 to announce the issue; presenters and panelists were Mark Smith of California HealthCare Foundation, Robert Berenson of The Urban Institute, Glenn Steele of Geisinger Health System, Richard Bohmer of Harvard Business School, and Susan Dentzer, the Editor-in-Chief of Health Affairs.